副主任技师/副教授, 硕士研究生导师，日本滨松医科大学医学博士，日本国立感染症研究所（NIID）访问学者，日本学术振兴会（JSPS）和笹川（SASAKAWA）医学奖学金资助对象，南昌市“洪燕领航”工程人选，2020年度“新时代赣鄱先锋”，现兼任江西省免疫学会理事，江西省微生物学会微生物检验专委会常委，江西省公共卫生领域专家库成员，江西省、广西科技项目评审专家，Front. Microbiol. 评审编委，iMeta，Infect. Dis. Res.，《微生物学报》杂志青年编委，长期从事病毒分子流行病学、系统进化基因组学以及肿瘤病毒分子免疫学研究。
主讲课程：《医学免疫学与病原生物学》、《医学统计学》
主要教育和研究经历
2016.4-2019.10 Hamamatsu University School of Medicine，病原生物学，博士
2007.9-2010.7 厦门大学生，微生物学，硕士
2014.5-2015.4 日本国立感染症研究所访问学者，从事肿瘤病毒分子免疫学研究
2010.7-2022.12 南昌市疾病预防控制中心检验科副科长，从事病原微生物系统进化、基因组流行病学研究
2022.12-至今 江西中医药大学病原微生物实验室（BSL-2）负责人
研究领域
病原微生物系统发育基因组学、肿瘤病毒分子生物学与免疫学、中药抗病毒分子机制。
科研项目
1) 国家自然科学基金委员会, 地区科学基金项目, 32360003, 在研, 主持。
2）江西省自然科学基金，面上项目，20242BAB25355，在研, 主持。
3) 江西省科技厅，重点研发计划，20192BBGL70008, 结题, 主持。
4) 江西中医药大学博士启动基金，2023BSZR001，在研，主持。
5) 日本学术振兴会, RONPAKU 项目, R11619, 结题, 主持。
6) 国家自然科学基金，地区基金项目，81460302, 参与（第六）。
7）江西省科技厅，重大项目，20161ACG70017，结题，参与（第四）。
8）南昌市科技局重点项目1项、一般项目1项，主持。
9）南昌市HCV基因型分布调查及分子流行病学研究，横20250030，在研，主持
学术成果
1) Zhou X#, Mo H#, Li H, He F and Yang Q*. Recent advances on coxsackievirus A6 vaccine research. Front. Immunol. 2025, 16:1603028.
2) 周显凤, 齐晓彤, 路亮, 艾勇, 冯长华. HIV/AIDS患者合并Merkel细胞多瘤病毒感染与激活的研究进展[J]. 肿瘤防治研究, 2025, 52(4): 331-336.
3) Zhou X, Yin C, Lin Z, Yan Z, Wang J. Merkel Cell Polyomavirus Co-Infection in HIV/AIDS Individuals: Clinical Diagnosis, Consequences and Treatments. Pathogens. 2025; 14(2):134.
4) He F#, Zhu C#, Wu X#, Yi L, Lin Z, Wen W, Zhu C, Tu J, Qian K, Li Q, Ma G, Li H, Wang F and Zhou X* Genomic surveillance reveals low-level circulation of two subtypes of genogroup C coxsackievirus A10 in Nanchang, Jiangxi Province, China, 2015–2023. Front. Microbiol. 2024, 15:1459917.
5) Zhou X*, Lin Z, Tu J, Zhu C and Li H. Persistent Predominance of the Victoria Lineage of Influenza B Virus during COVID-19 Epidemic in Nanchang, China. Influenza and Other Respiratory Viruses, 2023,17(12):e13226.
6) Zhou X#, Qian K#, Zhu C#, Yi L, Tu J, Yang S, Zhang Y, Zhang Y, Xia W, Ni X, Xu T, He F* and Li H*. Surveillance, epidemiology, and impact of the coronavirus disease 2019 interventions on the incidence of enterovirus infections in Nanchang, China, 2010-2022. Front. Microbiol. 2023, 14:1251683.
7) Zhou X*, Zhu C and Li H*. BK polyomavirus: latency, reactivation, diseases and tumorigenesis. Front. Cell. Infect. Microbiol, 2023, 13:1263983.
8) He F#, Rui J#, Deng Z#, Zhang Y, Qian K, Zhu C, Yu S, Tu J, Xia W, Zhu Q, Chen S, Chen T*, Zhou X*. Surveillance, epidemiology and impact of EV-A71 vaccination on hand, foot and mouth disease in Nanchang, China, 2010-2019. Front. Microbiol., 2022, 12 : 811553.
9) Yao J, Zhu Y, Zhang G, Zhou X, Shang H, Li L, Xu T, Action mechanisms and characteristics of miRNAs to regulate virus replication, Virology, 2024, 590: 109966.
10) Guo J, Song W, Ni X, Liu W, Wu J, Xia W, Zhou X, Wang W, He F, Wang X, Fan G, Zhou K, Chen H, Chen S. Pathogen change of avian influenza virus in the live poultry market before and after vaccination of poultry in southern China. Virology Journal, 2021,18.
11) Zhou X, Nakashima K, Ito M, et al. Prevalence and viral loads of polyomaviruses BKPyV, JCPyV, MCPyV, TSPyV and NJPyV and hepatitis viruses HBV, HCV and HEV in HIV-infected patients in China. Scientific Reports, 2020, 10:17066.
12) Zhou X, Bai H, Kataoka M, Ito M, Muramatsu M, Suzuki T, Li TC. Characterization of the self-assembly of New Jersey polyomavirus VP1 into virus-like particles and the virus seroprevalence in Japan. Scientific Reports, 2019, 9(1):13085.
13) Li TC, Yoshizaki S, Zhou X, Sentsui H, Shirato K, Matsuyama S, Melaku SK, Bazartseren B, Takeda N, Wakita T. Serological evidence of hepatitis E virus infection in dromedary camels in Ethiopia. Journal of Virological Methods. 2017, 246:34-37.
14) Li TC, Zhou X, Yoshizaki S, Ami Y, Suzaki Y, Nakamura T, Takeda N, Wakita T. Production of infectious dromedary camel hepatitis E virus by a reverse genetic system: Potential for zoonotic infection. Journal of Hepatology, 2016, 65(6):1104-1111.
15) Zhou X, Kataoka M, Liu Z, Takeda N, Wakita T, Li TC. Characterization of self-assembled virus-like particles of dromedary camel hepatitis e virus generated by recombinant baculoviruses. Virus Research, 2015, 210: 8-17.
16) Zhou X, Zhu Q, Xia W, He F, Hu M, Ni X, Gao M, Chen H, Chen S. Molecular epidemiology of an outbreak of hand, foot, and mouth disease associated with subgenotype C4a of enterovirus A71 in Nanchang, China in 2014. Journal of Medical Virology, 2015, 87:2154-2158.
17) Qi W#, Zhou X#, Shi W#, Huang L, Xia W, Liu D, Li H, Chen S, Lei F, Cao L, Wu J, He F, Song W, Li Q, Li H, Liao M, Liu M. Genesis of the novel human-infecting influenza A(H10N8) virus and potential genetic diversity of the virus in poultry, China. Eurosurveillance, 2014,19(25): 20841.
18) Zhou X*, Xia W, Tu J, Ni X. Molecular characterisation of enteroinvasive Escherichia coli O136:K78 isolates from patients of a diarrhoea outbreak in China. Indian Journal of Medical Microbiology, 2015, 33(4):528.
19) Chen H, Huang L, Li H, Zhou X, Li H, Sun N, Qi W, Xiao C, Ni X, Liu M, Liao M. High Pathogenicity of Influenza A (H10N8) Virus in Mice. Am J Trop Med Hyg, 2015 93(6):1360-3.
20) Ni X, He F, Hu M, Zhou X, Wang B, Feng C, Wu Y, Li Y, Tu J, Li H, Liu M, Chen H, Chen S. Investigation of avian influenza virus in poultry and wild birds due to novel avian-origin influenza A (H10N8) in Nanchang city, china. Microbes and Infection, 2015, 17(1): 48-53.
21) H Chen, H Yuan, R Gao, J Zhang, D Wang, Y Xiong, G Fan, F Yang, X Li, J Zhou, S Zou, L Yang, T Chen, L Dong, H Bo, X Zhao, Y Zhang, Y Lan, T Bai, J Dong, Q Li, S Wang, Y Zhang, H Li, T Gong, Y Shi, X Ni, J Li, J Zhou, J Fan, J Wu, X Zhou, M Hu, J Wan, W Yang, D Li, G Wu, Z Feng, George F Gao, Y Wang, Q Jin, M Liu, Y Shu. Clinical and epidemiological characteristics of a fatal case of avian influenza A H10N8 virus infection: a descriptive study. The Lancet, 2014, 383: 714-721. (IF2022=168.9, 一区Top)
22) Zhou X, Li H, Ni X, Liu M, Hu M, Wu J, Xia W, Yang S, Liu Y, Xiong Z, Chen H. Laboratory diagnosis and epidemiology of avian influenza A (H7N9) virus infection in humans in Nanchang City, China. Japanese Journal of Infectious Diseases, 2013; 66(6):558-60.
23) Zhou X*, Fan G, Xia W, He F, Hu M, Ni X, Zhang Y, Chen H. Molecular epidemiology of human enterovirus 71 strains in the Nanchang region of China in 2011. Japanese Journal of Infectious Diseases, 2013; 66(2):149-50.
24) Zhou X*, Fu S, Gao J, Chen H. Enterobacter sakazakii: an emerging foodborne pathogenic bacterium. Annals of Microbiology, 2012; 62(1): 1-5.
获奖
1）第十一届全国大学生医学创新大赛暨“一带一路”国际竞赛，预防医学赛道一等奖
2）肠道病毒EV71型毒力决定因子分子流行病学研究，2016年南昌市科技进步二等（排位第一）
3）南昌地区肠道病毒EV71型分子亚型特征研究，2013年南昌市科技进步三等奖（排位第一）
个人学术主页链接
Xianfeng Zhou (0000-0002-7756-9460) - ORCID
https://www.researchgate.net/profile/Xianfeng-Zhou
